Fucoidin

What is Fucoidan?

Fucoidan, a special intercellular polysaccharide, which exists in the cell wall matrix, is the unique biological activity matter in brown algae.

Compose of Fucoidan

We extract the fucoidan from the Laminaria japonicia. The product, which is hydrosolubleheteropolysaccharide, mainly consists of sulfuric ester- Fucose, and also have little quantities of galactose, Mannose, xylose, arabinose, saccharic-aldehyded acid. So it’s also called algin or fucoidan & laminaran, the major effective ingredient is α-L-fucose-4-sulfuric ester.

Fuction of Fucoidan. And how does Fucoidan work?

Fucoidan is an excellent raw material of health-foods and drug medicine. Because of natural Organic sulfate radical, it has characteristic of high molecular compound containing the negative ion. Studies showed that it have many physiologically actives, such as inhibiting blood clotting, lowering the blood fats, repelling chronic renal-failure, anti-tumor, anti-virus, regenerating tissue, Suppressing gastric ulcer, enhancing bodies’ immunity, etc.

How does Fucoidan work?

Fucoidan is an immunomodulator which have immediate effects on Macrophage and T-cell,with obvious pharmacological activities of inhibiting blood clotting and promoting fibrinolysis. Fucose or its degradative offspring can induce cancer-cells-apoptosis, so it can be used on revulsant and anticancer-drug. The generation of Cytokines-growth can help all kinds of cells to grow , repair the damaged tissue and an organ or tissue functions failure.Because polysaccharides has the anticoagulant effect, which vails the patient who has hyper-blood-viscosity, it can be made to drugs and health products in counteracting or preventing the thrombos It also has an efficacy against lowering cholesterol levels and blood sugar levels, can overcome side effects of normal medicine. It can be used in treatment ofchronic renal failure, especially in an early phase, improving the functions of renaland enhancing creatinine clearance. It also can be used as cements and reduction additives of metallic ion. For example, It can abate the absorption of Pb by 70%.

Safety data of Fucoidan

The general pharmacology research indicated: the dose of 100mg/Kg, 300mg/Kg medicine to doped up dog, the dog had no obviouse effects on blood pressure and. heart-electricity.400mg/Kg,800mg/Kg had no obviouse effects on Mouse nervous system. The acute toxicitytest indicated that, Mouse intravenous injection LD₅₀ is 515.3±39.8 mg/Kg; The little mouse fills the stomach with medicine LD₅₀> 4g/Kg, the big mouse fills the stomach with medicine LD₅₀> 4g/Kg.

AMES showed that Fucoidan do not have sudden change effection on the gene.

Quality Standard for Fucoidan